Persistent organic pollutants in adipose tissue should be considered in obesity research

Toxicological Function of Adipose Tissue: Focus on Persistent Organic Pollutants

BACKGROUND Adipose tissue (AT) is involved in several physiological functions, including metabolic regulation, energy storage, and endocrine functions. OBJECTIVES In this review we examined the evidence that an additional function of AT is to modulate persistent organic pollutant (POP) toxicity through several mechanisms. METHODS We reviewed the literature on the interaction of AT with POPs...

Staphylococcus lugdunensis; a pathogen that should be considered in Iran

Background: Staphylococcus lugdunensis is Gram-positive cocci of the staphylococcaceae family. S. lugdunensis despite having a clotting factor (wall coagulase), was classified in the coagulase negative staphylococcus group (CoNS) for lack of free coagulase. Although this bacterium is part of the human normal flora, in terms of virulence, S. lugdunensis is in second place after S. aureus. S. lug...

Adipose Tissue Pollutants and Obesity

Current Status and Regulatory Aspects of Pesticides Considered to be Persistent Organic Pollutants (POPs) in Taiwan

Organochlorine pesticides (OCPs) are capable of persisting in the environment, transporting between phase media and accumulating to high levels, implying that they could pose a risk of causing adverse effects to human health and the environment. Consequently, most OCPs are designated as persistent organic pollutants (POPs) and even as endocrine disrupting chemicals (EDCs). The objective of this...

Expression of Obesity Markers and Persistent Organic Pollutants Levels in Adipose Tissue of Obese Patients: Reinforcing the Obesogen Hypothesis?

INTRODUCTION Persistent Organic Pollutants (POPs) accumulate in adipose tissue and some are described to possess endocrine disrupting capacities. Therefore, it is important to evaluate their effects on key endocrine pathways in adipose tissue (AT), to further evaluate their potential role in metabolic pathologies such as obesity. OBJECTIVES THE AIM IS TWOFOLD: (i) evaluate gene expression lev...